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TMS Effectiveness

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TMS Effectiveness

Clinical trials have demonstrated the effectiveness of NeuroStar TMS Therapy in treating patients who have not benefited from prior antidepressant medication. NeuroStar TMS Therapy was studied in adult patients suffering from Major Depressive Disorder, all of whom had not received satisfactory improvement with previous treatments.

An Effective and Durable Option for Treating Major Depressive Disorder

In an independent, randomized, controlled trial funded by the National Institute of Mental Health, 307 patients were treated with the NeuroStar TMS System for 4 to 6 weeks, similar to real clinical context.1

Patients were divided into two groups:

  • Low Treatment Resistance: Patients who have failed to improve their depression symptoms after a single antidepressant treatment of adequate dose and duration.
  • High Treatment Resistance: Patients who have failed to improve their depression symptoms after a multiple (2-14) antidepressant treatments of adequate dose and duration.

At the end of their treatments, patients who had received NeuroStar TMS Therapy were four times more likely to achieve remission compared to patients receiving a sham treatment. 1 in 2 patients experienced significant improvement in their depression symptoms and 1 in 3 experienced complete remission. Patients treated with the NeuroStar TMS System also experienced significant improvement in anxiety and physical symptoms (such as appetite changes, aches and pains, and lack of energy) associated with depression.1

Durability of TMS Treatments

NeuroStar TMS is the only TMS system with the durability of its effects established over 12 months.

In a trial with physician directed standard of care, meaning TMS Therapy could be used in conjunction with antidepressants as needed, patients who had received treatment then reported their symptom levels at 3, 6, 9 and 12 months to determine the durability of their treatments. By the end of the 12-month period, 2 out of 3 patients who had either responded or completely remitted after TMS treatment remained at the symptom levels they reported at the end of the treatment phase.1

After the end of the treatment period, only 1 in 3 patients needed to come back for maintenance TMS sessions, or ‘reintroduction’ during this 12-month period.1

Treatment Algorithm

Additionally, Neuronetics has developed a new tool to use in educating patients on the best practices of treating depression. The Best Practices Treatment Guideline for Depression has been developed to help patients understand TMS Therapy as an option if their first line antidepressant medications stop working. This guideline is based on the 2010 American Psychiatric Association’s practice guidelines and NeuroStar TMS Therapy indication for use, which says:

NeuroStar TMS Therapy is indicated for the treatment of major depressive disorder in adult patients who have failed to achieve satisfactory improvement from prior antidepressant medication at or above the minimal effective dose and duration in the current episode.

Please see the Treatment Algorithm for an effective illustration of the use of NeuroStar TMS Therapy early on in the treatment of depression.

NeuroStar TMS Therapy has not been studied in patients who have not received prior antidepressant treatment.

View TMS Therapy safety data

TMS+YOU is an online community and national patient advocacy site for TMS Therapy. Those considering Transcranial Magnetic Stimulation can connect with patients who have had the treatment to answer questions, share insights, and get the latest information.

References:

  1. Carpenter LL, et al. (2012). Depress Anxiety, 29(7):587-596.

Is TMS Therapy an Effective Treatment for Depression?

Have you sought treatment for your depression only to find unsatisfactory results? NeuroStar TMS Therapy® has been clinically proven to improve symptoms of depression.

Depression & TMS >>

What is Transcranial Magnetic Stimulation?

Transcranial Magnetic Stimulation, TMS Therapy, uses short pulses of magnetic fields to stimulate nerve cells in one of the areas of the brain thought to control mood.

Transcranial Magnetic Stimulation >>

Is Neurostar TMS Therapy Safe?

Clinical trials have proven the safety of NeuroStar TMS Therapy® in treating patients who’ve had an inadequate response to prior antidepressant medications.

Neurostar TMS Therapy >>

DFW TMS

Address:
2820 Village Pkwy., Suite 620
Highland Village, TX 75077

Phone:
(972) 317-2082

Serving:

Highland Village, TX
Dallas, TX
Fort Worth, TX
Flower Mound, TX
Coppell, TX
Grapevine, TX
Southlake, TX
Trophy Club, TX
Keller, TX
Roanoke, TX
Argyle, TX
Robson Ranch, TX
Denton, TX